Objective: To describe the clinicopathological characteristics and prognosis of intrahepatic biliary cystic tumor (IBCT) and compare the difference betwwen male and female patients.
Methods: 11 male and 45 female patients with histological confirmed IBCT from January 2003 to April 2014 were envolved. clinical characteristics, laboratory examination, radiological features, treatment method and prognosis were analyzed.
Results: The mean age of male patients with IBCT was significantly older than that of female patients (54.9±10.1 years vs 46.2±12.9 years, P=0.041). There were no significant differences in radiological features between male and female patients except for mural nodules (10/11 vs 15/45, P=0.001). Intrahepatic biliary cystadenocarcinoma (IBC) was more common in male patients than female patients (8/11 vs 16/45, P=0.041). Male patients had worse prognosis than female patients (P=0.014). 1-year, 3-year, and 5-year survival of male patients was 90.9%,45.5%,30.3%, respectively. However, 1-year, 3-year, and 5-year survival of female patients was 94.8%,82.7%,78.6%.
Conclusions: Male patients had low incidence of IBCT, and were more common for IBC. Even with complete resection, the long-term survival was still poor, close follow-up were recommended especially for male patients.