RETRACTED: Ambient UV-B exposure reduces the binding of ofloxacin with bacterial DNA gyrase and induces DNA damage mediated apoptosis

Jyoti Singh; Ashish Dwivedi; Syed Faiz Mujtaba; Krishna P Singh; Manish Kumar Pal; Deepti Chopra; Shruti Goyal; Ajeet K Srivastav; Divya Dubey; Shailendra K Gupta; Chandana Haldar; Ratan Singh Ray

doi:10.1016/j.biocel.2016.01.001

RETRACTED: Ambient UV-B exposure reduces the binding of ofloxacin with bacterial DNA gyrase and induces DNA damage mediated apoptosis

Int J Biochem Cell Biol. 2016 Apr:73:111-126. doi: 10.1016/j.biocel.2016.01.001. Epub 2016 Jan 23.

Authors

Affiliations

¹ Photobiology Laboratory, Systems Toxicology and Health Risk Assessments Group CSIR-Indian Institute of Toxicology Research (CSIR-IITR), MG Marg, Lucknow 226001, Uttar Pradesh, India; Academy of Scientific and Innovative Research, CSIR-IITR Campus, Lucknow, India.
² Photobiology Laboratory, Systems Toxicology and Health Risk Assessments Group CSIR-Indian Institute of Toxicology Research (CSIR-IITR), MG Marg, Lucknow 226001, Uttar Pradesh, India; Pineal Research Lab., Department of Zoology, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.
³ Photobiology Laboratory, Systems Toxicology and Health Risk Assessments Group CSIR-Indian Institute of Toxicology Research (CSIR-IITR), MG Marg, Lucknow 226001, Uttar Pradesh, India.
⁴ Bioinformatics Centre, Systems Toxicology and Health Risk Assessments Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), MG Marg, Lucknow 226001, Uttar Pradesh, India.
⁵ Department of Obstetrics and Gynecology, King George's Medical University, Lucknow 226001, Uttar Pradesh, India.
⁶ Bioinformatics Centre, Systems Toxicology and Health Risk Assessments Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), MG Marg, Lucknow 226001, Uttar Pradesh, India; Department of Systems Biology& Bioinformatics, University of Rostock, Rostock 1805, Germany.
⁷ Pineal Research Lab., Department of Zoology, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.
⁸ Photobiology Laboratory, Systems Toxicology and Health Risk Assessments Group CSIR-Indian Institute of Toxicology Research (CSIR-IITR), MG Marg, Lucknow 226001, Uttar Pradesh, India; Academy of Scientific and Innovative Research, CSIR-IITR Campus, Lucknow, India. Electronic address: rsray@iitr.res.in.

PMID: 26812543
DOI: 10.1016/j.biocel.2016.01.001

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. The study is retracted due to image duplication reasons: The article contains an image that had already appeared in Free Radic Res, 48.3 (2014): 333–346. DOI 10.3109/10715762.2013.869324. The images are used in both papers but to conclude something entirely different, and suggested that the images have an entirely different biological meaning and treatment. Duplicating images in this way is ethically not acceptable.

Keywords: Apoptosis; DNA damage; DNA gyrase; OFLX; UV-B.

Publication types

Research Support, Non-U.S. Gov't
Retracted Publication

MeSH terms

Apoptosis / radiation effects
DNA Damage / radiation effects
DNA Gyrase / metabolism*
DNA, Bacterial / radiation effects
Ofloxacin / metabolism*
Protein Binding / radiation effects
Ultraviolet Rays*

Substances

DNA, Bacterial
Ofloxacin
DNA Gyrase