KIR and HLA genotyping of Japanese descendants from Curitiba, a city of predominantly European ancestry from Southern Brazil

Danillo G Augusto; Leonardo M Amorim; Ticiana D J Farias; Maria Luiza Petzl-Erler

doi:10.1016/j.humimm.2016.01.011

KIR and HLA genotyping of Japanese descendants from Curitiba, a city of predominantly European ancestry from Southern Brazil

Hum Immunol. 2016 Apr;77(4):336-7. doi: 10.1016/j.humimm.2016.01.011. Epub 2016 Jan 21.

Authors

Danillo G Augusto¹, Leonardo M Amorim², Ticiana D J Farias², Maria Luiza Petzl-Erler³

Affiliations

¹ Laboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba CEP 81531-980, Brazil. Electronic address: danillo@augusto.bio.br.
² Laboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba CEP 81531-980, Brazil.
³ Laboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba CEP 81531-980, Brazil. Electronic address: perler@ufpr.br.

PMID: 26805458
DOI: 10.1016/j.humimm.2016.01.011

Abstract

We hereby report the KIR gene frequencies and the frequencies of HLA ligands of KIR for Brazilians of Japanese ancestry. A total of 51 individuals were genotyped for presence/absence of KIR (killer cell immunoglobulin-like receptors) genes and presence of HLA (human leukocyte antigens) ligands. KIR was genotyped using two pairs of sequence-specific primers (PCR-SSP) and HLA ligands were typed by LABType® SSO reagent kits (One Lambda, USA). These data are fully available in Allele Frequencies Net Database, under the population name "Brazil Curitiba Japanese KIR".

Keywords: Brazil; Frequencies; Killer cell immunoglobulin-like receptors; Population genetics.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Brazil / epidemiology
Ethnicity / genetics*
Gene Frequency
Genotype
HLA Antigens / genetics*
Humans
Receptors, KIR / genetics*

Substances

HLA Antigens
Receptors, KIR