High-grade Carcinoma of the Proximal Ureter With Negative Nephroureteroscopy Detected by a Positive FISH Test: A Rare Case Report

Guoxian Zhang; Daniel Steinbach; Miezcyslaw Gajda; Tobias Franiel; Marc-Oliver Grimm; Marcus Horstmann

doi:10.1016/j.eucr.2015.06.009

High-grade Carcinoma of the Proximal Ureter With Negative Nephroureteroscopy Detected by a Positive FISH Test: A Rare Case Report

Urol Case Rep. 2015 Jul 11;3(5):167-9. doi: 10.1016/j.eucr.2015.06.009. eCollection 2015 Sep.

Authors

Guoxian Zhang¹, Daniel Steinbach², Miezcyslaw Gajda³, Tobias Franiel⁴, Marc-Oliver Grimm², Marcus Horstmann²

Affiliations

¹ Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Department of Urology, Friedrich Schiller University, Jena, Germany.
² Department of Urology, Friedrich Schiller University, Jena, Germany.
³ Institute of Pathology, Friedrich Schiller University, Jena, Germany.
⁴ Institute of Radiology, Friedrich Schiller University, Jena, Germany.

Abstract

Upper tract urothelial carcinomas in the proximal ureter are an uncommon disease. We present a case in which it was firstly detected by fluorescence in situ hybridization and not by endoscopy and radiologic imaging. Consequently, a radical nephroureterectomy with excision of the bladder cuff was performed as the gold standard treatment.

Keywords: Cyt, cytology; Cytology; FISH, fluorescence in situ hybridization; Fluorescence in situ hybridization; UTUC, Upper tract urothelial carcinomas; Ureter; Urothelial carcinoma.

Publication types

Case Reports