Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

Nature. 1989 Sep 28;341(6240):299-303. doi: 10.1038/341299a0.

Abstract

The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Chromosomes, Fungal
  • Cloning, Molecular*
  • DNA, Fungal / genetics
  • Gene Expression
  • Genes*
  • Genes, Fungal*
  • Molecular Sequence Data
  • Promoter Regions, Genetic*
  • Protein Binding
  • RNA, Messenger / analysis
  • RNA, Messenger / genetics
  • Saccharomyces cerevisiae / genetics*
  • Sequence Homology, Nucleic Acid
  • Transcription Factor TFIID
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism
  • Transcription, Genetic

Substances

  • DNA, Fungal
  • RNA, Messenger
  • Transcription Factor TFIID
  • Transcription Factors

Associated data

  • GENBANK/X16860