Assessment of pediatric obstructive sleep apnea using a drug-induced sleep endoscopy rating scale

Laryngoscope. 2016 Jun;126(6):1492-8. doi: 10.1002/lary.25842. Epub 2016 Jan 17.

Abstract

Objectives/hypothesis: Assess the reliability of a Sleep Endoscopy Rating Scale (SERS) and its relationship with pediatric obstructive sleep apnea (OSA) severity.

Study design: Retrospective case series of pediatric patients who underwent drug-induced sleep endoscopy (DISE) at the time of surgery for OSA from January 1, 2013 to May 1, 2014.

Methods: Three blinded otolaryngologists scored obstruction on DISE recordings as absent (0), partial (+1), or complete (+2) at six anatomic levels: nasal airway, nasopharynx, velopharynx, oropharynx, hypopharynx, and arytenoids. Ratings were summed for a SERS total score (range, 0-12). Reliability was calculated using a κ statistic with linear weighting. SERS ratings and obstructive apnea-hypopnea index (OAHI) were compared using Spearman correlation. A receiver operating characteristic (ROC) analysis determined the ability of the SERS total score to predict severe OSA (OAHI >10).

Results: Thirty-nine patients were included (mean age, 8.3 ± 5.1 years; 36% obese; mean OAHI, 19.1 ± 23.7). Intrarater and inter-rater reliability was substantial-to-excellent (κ = 0.61-0.83) and fair-to-substantial (κ = 0.33-0.76), respectively. Ratings correlated best with OAHI for the oropharynx (r = 0.54, P = .02), hypopharynx (r = 0.48, P = .04), and SERS total score (r = 0.75, P = .002). In ROC analysis, a SERS total score ≥6 demonstrated sensitivity/specificity of 81.8%/87.5%, respectively, and correctly classified 84% of patients.

Conclusions: The SERS can be applied reliably in children undergoing DISE for OSA. Ratings of the oropharynx, hypopharynx, and SERS total score demonstrated significant correlation with OSA severity. A SERS total score ≥6 was an accurate predictor of severe OSA.

Level of evidence: 4. Laryngoscope, 126:1492-1498, 2016.

Keywords: Pediatric sleep apnea; adenotonsillectomy; drug-induced sleep endoscopy; obstructive sleep apnea.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Endoscopy / methods
  • Endoscopy / statistics & numerical data*
  • Female
  • Humans
  • Infant
  • Male
  • Observer Variation
  • Pharynx / physiopathology
  • Polysomnography / methods
  • Polysomnography / statistics & numerical data*
  • ROC Curve
  • Reproducibility of Results
  • Retrospective Studies
  • Severity of Illness Index*
  • Sleep Apnea, Obstructive / diagnosis*
  • Statistics, Nonparametric
  • Symptom Assessment / methods
  • Symptom Assessment / statistics & numerical data*