Beak and feather disease virus genotypes in Australian parrots reveal flexible host-switching

Aust Vet J. 2015 Dec;93(12):471-5. doi: 10.1111/avj.12389.

Abstract

Objective: To discover beak and feather disease virus (BFDV) genotypes in Australian parrots that might threaten vulnerable and endangered psittacine bird species.

Methods: Phylogenetic analyses of new DNA sequence data from Australian birds including the Rep gene (n = 55) and nine whole genomes, were compared with all available published BFDV genomes to assess host- and geographically-based divergence as well as probable host-switch events.

Results: Strong support for flexible host-switching and recombination was detected, indicating active cross-species transmission in various subpopulations.

Conclusion: The data suggested that all endangered Australian psittacine bird species are equally likely to be infected by BFDV genotypes from any other close or distantly related host reservoir species.

Keywords: birds; circovirus; host generalism; key threatening process; psittacine beak and feather disease; viral quasispecies; viral recombination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Australia
  • Circoviridae Infections / genetics
  • Circoviridae Infections / virology*
  • Circovirus / genetics*
  • DNA Barcoding, Taxonomic / veterinary
  • Databases, Nucleic Acid
  • Genetic Variation
  • Genome
  • Genotype
  • Polymerase Chain Reaction
  • Psittaciformes / virology*
  • Sequence Analysis, DNA