Secondary orthostatic tremor in the setting of cerebellar degeneration

Harini Sarva; William Lawrence Severt; Nuri Jacoby; Seth L Pullman; Rachel Saunders-Pullman

doi:10.1016/j.jocn.2015.10.027

Secondary orthostatic tremor in the setting of cerebellar degeneration

J Clin Neurosci. 2016 May:27:173-5. doi: 10.1016/j.jocn.2015.10.027. Epub 2016 Jan 4.

Authors

Harini Sarva¹, William Lawrence Severt², Nuri Jacoby³, Seth L Pullman⁴, Rachel Saunders-Pullman⁵

Affiliations

¹ Department of Neurology, Division of Movement Disorders, Mount Sinai Beth Israel, 10 Union Square East, New York, NY 10003, USA. Electronic address: sarvaharini@gmail.com.
² Department of Neurology, Division of Movement Disorders, Mount Sinai Beth Israel, 10 Union Square East, New York, NY 10003, USA.
³ Department of Neurology, Maimonides Medical Center, Brooklyn, NY, USA.
⁴ The Neurological Institute, Columbia University Medical Center, New York, NY, USA.
⁵ Department of Neurology, Division of Movement Disorders, Mount Sinai Beth Israel, 10 Union Square East, New York, NY 10003, USA; Department of Neurology, Icahn School of Medicine, Mount Sinai Medical Center, New York, NY, USA.

PMID: 26765757
DOI: 10.1016/j.jocn.2015.10.027

Abstract

Orthostatic tremor (OT) and cerebellar ataxia are uncommon and difficult to treat. We present two patients with OT and cerebellar degeneration, one of whom had spinocerebellar ataxia type 2 and a good treatment response.

Keywords: Ataxia; Gait disturbance; Orthostatic tremor; SCA-2.

Publication types

Case Reports

MeSH terms

Adrenergic beta-Antagonists / therapeutic use
Aged, 80 and over
Brain / pathology
Cognition
Gait Disorders, Neurologic / etiology
Humans
Male
Middle Aged
Neuropsychological Tests
Propranolol / therapeutic use
Spinocerebellar Ataxias / etiology
Spinocerebellar Ataxias / psychology
Spinocerebellar Degenerations / complications*
Spinocerebellar Degenerations / psychology
Treatment Outcome
Tremor / etiology*

Substances

Adrenergic beta-Antagonists
Propranolol