Diabetic Wounds Exhibit Distinct Microstructural and Metabolic Heterogeneity through Label-Free Multiphoton Microscopy

J Invest Dermatol. 2016 Jan;136(1):342-344. doi: 10.1038/JID.2015.371.

Authors

Kyle P Quinn¹, Ermelindo C Leal², Ana Tellechea², Antonios Kafanas², Michael E Auster², Aristidis Veves², Irene Georgakoudi³

Affiliations

¹ Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, USA; Department of Biomedical Engineering, University of Arkansas, Fayetteville, Arkansas, USA. Electronic address: kyle@quinnlab.org.
² Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
³ Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, USA.

No abstract available

Publication types

Comparative Study
Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Biopsy, Needle
Case-Control Studies
Diabetes Complications / diagnosis
Diabetes Complications / pathology*
Epidermis / metabolism
Epidermis / ultrastructure*
Female
Humans
Immunohistochemistry
Male
Microscopy, Fluorescence, Multiphoton / methods*
Oxidation-Reduction
Reference Values
Sampling Studies
Severity of Illness Index
Skin Ulcer / diagnosis*
Skin Ulcer / etiology
Wound Healing / physiology*

Grants and funding