Malignant transformation of residual posterior fossa epidermoid cyst to squamous cell carcinoma

Br J Neurosurg. 2017 Aug;31(4):497-498. doi: 10.3109/02688697.2015.1125445. Epub 2016 Jan 13.

Abstract

Malignant transformation of intracranial epidermoid cysts to squamous cell carcinoma is a rare occurrence and only a small number have been reported to date. MRI recurrence in combination with neurological decline should prompt surgery to exclude malignant transformation. Herein, we describe our experience of such a case and contribute to the evolving series within the literature.

Keywords: CP angle; epidermoid cyst; malignant transformation; squamous cell carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / pathology*
  • Cell Transformation, Neoplastic / pathology
  • Cerebellar Diseases / pathology*
  • Cerebellopontine Angle / pathology*
  • Cranial Fossa, Posterior
  • Epidermal Cyst / pathology*
  • Epidermal Cyst / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology
  • Trigeminal Neuralgia / etiology