Behaviour of spirotetramat residues and its four metabolites in citrus marmalade during home processing

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33(3):452-9. doi: 10.1080/19440049.2015.1137638. Epub 2016 Jan 29.

Abstract

The effect of home processing on the residues of spirotetramat and its four metabolites (B-enol, B-glu, B-mono and B-keto) in citrus marmalade is comprehensively investigated in this paper by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). A five-fold recommended dose of spirotetramat was applied to citrus fruit under field conditions and the processing included five steps: washing, peeling, pre-treatment for peel, mixing and boiling. The results showed that spirotetramat was the predominant component detected in unprocessed citrus, accounting for 64%. All the detected residues were primarily deposited on citrus peel, except for B-enol which was also present in the citrus pulp. Washing reduced spirotetramat, B-enol, B-glu and B-keto by 83%, 56%, 41% and 16%, respectively, and pre-treatment of the peel removed between 42% and 68% of the residues. Four compounds were all below the limit of detection after the mixing step. In the final product, only B-keto was detected at the concentration of 0.010 mg kg(-1). After the whole process, the processing factors for spirotetramat, B-enol, B-glu and B-keto were < 0.041, < 0.125, < 0.294 and 0.313, respectively, which indicated that home processing can significantly reduce residues of spirotetramat and its metabolites in citrus marmalade.

Keywords: Citrus; LC-MS; home processing; metabolites; spirotetramat.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aza Compounds / analysis*
  • Aza Compounds / metabolism*
  • Chromatography, High Pressure Liquid
  • Citrus / chemistry*
  • Citrus / metabolism
  • Environmental Monitoring
  • Food Handling*
  • Molecular Structure
  • Pesticide Residues / analysis*
  • Pesticide Residues / metabolism
  • Spiro Compounds / analysis*
  • Spiro Compounds / metabolism*
  • Tandem Mass Spectrometry

Substances

  • Aza Compounds
  • Pesticide Residues
  • Spiro Compounds
  • spirotetramat