Famous

Surv Ophthalmol. 2016 Jul-Aug;61(4):512-9. doi: 10.1016/j.survophthal.2015.12.008. Epub 2015 Dec 29.

Abstract

A 62-year-old woman with multiple sclerosis experienced painless loss of vision in both eyes after starting fingolimod. Fundus examination revealed bilateral macular edema confirmed by optical coherence tomography. Fingolimod was discontinued, and a topical nonsteroidal inflammatory drug and corticosteroid were initiated. Within 2 months, vision returned to baseline with complete resolution of the macular edema.

Keywords: disease-modifying agents; fingolimod; macular edema; multiple sclerosis; optic neuritis; sphingosine-1-phosphate.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Fingolimod Hydrochloride / adverse effects*
  • Fingolimod Hydrochloride / therapeutic use
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Macula Lutea / drug effects
  • Macula Lutea / pathology*
  • Macular Edema / chemically induced*
  • Macular Edema / diagnosis
  • Middle Aged
  • Multiple Sclerosis / drug therapy*
  • Tomography, Optical Coherence / methods*

Substances

  • Immunosuppressive Agents
  • Fingolimod Hydrochloride