Pyogenic spondylodiscitis following anti-interleukin-6 therapy in a patient with rheumatoid arthritis (implication of hematogenous infection risk in degenerative intervertebral discs): A case report and review of the literature

J Orthop Sci. 2016 Sep;21(5):694-7. doi: 10.1016/j.jos.2015.06.018. Epub 2015 Jun 30.

Authors

Takeru Tsujimoto¹, Masahiko Takahata², Terufumi Kokabu¹, Megumi Matsuhashi³, Norimasa Iwasaki¹

Affiliations

¹ Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan.
² Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan. Electronic address: takamasa@med.hokudai.ac.jp.
³ Hokkaido Medical Center for Rheumatic Diseases, Sapporo, 063-0811, Japan.

PMID: 26740426
DOI: 10.1016/j.jos.2015.06.018

No abstract available

Publication types

Case Reports
Review

MeSH terms

Abscess / diagnostic imaging
Abscess / microbiology
Abscess / therapy*
Aged
Anti-Bacterial Agents / therapeutic use
Antibodies, Monoclonal, Humanized / adverse effects*
Antibodies, Monoclonal, Humanized / therapeutic use
Arthritis, Rheumatoid / complications
Arthritis, Rheumatoid / diagnostic imaging
Arthritis, Rheumatoid / drug therapy*
Combined Modality Therapy
Debridement / methods
Discitis / diagnostic imaging*
Discitis / etiology
Discitis / therapy
Female
Follow-Up Studies
Humans
Interleukin-6 / antagonists & inhibitors*
Intervertebral Disc Degeneration / diagnostic imaging*
Intervertebral Disc Degeneration / etiology
Magnetic Resonance Imaging / methods
Risk Assessment
Spondylitis / diagnostic imaging
Spondylitis / therapy
Treatment Outcome

Substances

Anti-Bacterial Agents
Antibodies, Monoclonal, Humanized
Interleukin-6
tocilizumab