Relearning to See in Cortical Blindness

Neuroscientist. 2016 Apr;22(2):199-212. doi: 10.1177/1073858415621035. Epub 2015 Dec 10.

Abstract

The incidence of cortically induced blindness is increasing as our population ages. The major cause of cortically induced blindness is stroke affecting the primary visual cortex. While the impact of this form of vision loss is devastating to quality of life, the development of principled, effective rehabilitation strategies for this condition lags far behind those used to treat motor stroke victims. Here we summarize recent developments in the still emerging field of visual restitution therapy, and compare the relative effectiveness of different approaches. We also draw insights into the properties of recovered vision, its limitations and likely neural substrates. We hope that these insights will guide future research and bring us closer to the goal of providing much-needed rehabilitation solutions for this patient population.

Keywords: V1; perceptual learning; stroke; vision loss; vision rehabilitation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blindness, Cortical / diagnostic imaging
  • Blindness, Cortical / physiopathology*
  • Blindness, Cortical / rehabilitation*
  • Humans
  • Learning / physiology*
  • Recovery of Function / physiology*
  • Visual Cortex / diagnostic imaging
  • Visual Fields / physiology