A baby with a lot of nerve

Hema L Ramkumar; Rohan Verma; Janet Crow; Shira Robbins; David B Granet; Claire A Sheldon; Fred M Henretig; Grant T Liu

doi:10.1016/j.survophthal.2015.11.007

A baby with a lot of nerve

Surv Ophthalmol. 2016 Jul-Aug;61(4):506-11. doi: 10.1016/j.survophthal.2015.11.007. Epub 2015 Nov 30.

Authors

Hema L Ramkumar¹, Rohan Verma², Janet Crow³, Shira Robbins⁴, David B Granet⁵, Claire A Sheldon⁶, Fred M Henretig⁷, Grant T Liu⁸

Affiliations

¹ Department of Ophthalmology, University of California, San Diego, San Diego, California, USA.
² School of Medicine, University of California, San Diego, San Diego, California, USA.
³ Department of Pediatrics, University of California, San Diego, California, USA.
⁴ Pediatric Ophthalmology and Adult Re-Alignment Services, Ratner Children's Eye Center & Shiley Eye Institute, University of California, San Diego, San Diego, California, USA.
⁵ Pediatric Ophthalmology and Adult Re-Alignment Services, Ratner Children's Eye Center & Shiley Eye Institute, University of California, San Diego, San Diego, California, USA. Electronic address: dgranet@ucsd.edu.
⁶ Division of Neuro-Ophthalmology, Department of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
⁷ Section of Clinical Toxicology, Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
⁸ Neuro-ophthalmology Service, Division of Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

PMID: 26656927
DOI: 10.1016/j.survophthal.2015.11.007

Abstract

An infant presented with bilateral disk edema and an acute left sixth cranial nerve (CN VI) palsy because of pseudotumor cerebri (PTC). PTC is rare in infants where it is often associated with endocrine abnormalities, medications, viral infections, systemic conditions, and nutritional etiologies such as vitamin A toxicity. We report a case of PTC in an infant associated with hypervitaminosis A with an unlikely source-a common prenatal vitamin.

Keywords: acetazolamide; cranial neuropathy; idiopathic intracranial hypertension; infant; pseudotumor cerebri; vitamin A.

Publication types

Case Reports

MeSH terms

Diagnosis, Differential
Female
Humans
Hypervitaminosis A / complications*
Infant
Magnetic Resonance Imaging
Optic Nerve / diagnostic imaging*
Pseudotumor Cerebri / diagnosis*
Pseudotumor Cerebri / etiology
Vitamin A / adverse effects*
Vitamins / adverse effects

Substances

Vitamins
Vitamin A