The ribonucleoside diphosphate reductase gene (nrdA) of Escherichia coli carries a repetitive extragenic palindromic (REP) sequence in its 3' structural terminus

Mol Microbiol. 1989 Jun;3(6):839-41. doi: 10.1111/j.1365-2958.1989.tb00232.x.

Abstract

A computer search for repeated sequences led us to identify five REP (repetitive extragenic palindromic) sequences in the 3'-terminal region of the Escherichia coli ribonucleoside diphosphate reductase gene (nrdA). These REP sequences are located within a putative duplicated DNA region, the first of them being part of the carboxy-terminal coding region of the nrdA gene. This is the first report of a REP sequence within a structural gene and also the first example of a REP sequence apparently generated by DNA duplication.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • DNA, Bacterial
  • Escherichia coli / enzymology
  • Escherichia coli / genetics*
  • Genes
  • Genes, Bacterial*
  • Molecular Sequence Data
  • Repetitive Sequences, Nucleic Acid*
  • Ribonucleoside Diphosphate Reductase / genetics*
  • Ribonucleotide Reductases / genetics*

Substances

  • DNA, Bacterial
  • Ribonucleotide Reductases
  • Ribonucleoside Diphosphate Reductase

Associated data

  • GENBANK/UNKNOWN