Nanotechnology in the Fabrication of Protein Microarrays

Manuel Fuentes; Paula Díez; Juan Casado-Vela

doi:10.1007/978-1-4939-3136-1_14

Nanotechnology in the Fabrication of Protein Microarrays

Methods Mol Biol. 2016:1368:197-208. doi: 10.1007/978-1-4939-3136-1_14.

Authors

Manuel Fuentes¹, Paula Díez², Juan Casado-Vela³

Affiliations

¹ Proteomics Unit, Department of Medicine and General Cytometry Service-Nucleus, Cancer Research Center/IBMCC (USAL/CSIC) - IBSAL, University of Salamanca, 37007, Salamanca, Spain. mfuentes@usal.es.
² Proteomics Unit, Department of Medicine and General Cytometry Service-Nucleus, Cancer Research Center/IBMCC (USAL/CSIC) - IBSAL, University of Salamanca, 37007, Salamanca, Spain.
³ Spanish National Research Council (CSIC) - Spanish National Biotechnology Centre (CNB), Darwin 3, Cantoblanco, 28049, Madrid, Spain. jcasado@cnb.csic.es.

PMID: 26614077
DOI: 10.1007/978-1-4939-3136-1_14

Abstract

Protein biochips are the heart of many medical and bioanalytical applications. Increasing interest of protein biochip fabrication has been focused on surface activation and subsequent functionalization strategies for the immobilization of these molecules.

Keywords: Microarrays; Oriented immobilization; Pin materials; Sample deposition; Surface activation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Metals / chemistry
Nanotechnology / methods*
Protein Array Analysis / methods*
Silicon Dioxide / chemistry
Surface Properties

Substances

Metals
Silicon Dioxide