Outbreak in newborns of methicillin-resistant Staphylococcus aureus related to the sequence type 5 Geraldine clone

Camille Leroyer; Philippe Lehours; Anne Tristan; Frederique Boyer; Veronique Marie; Christophe Elleau; Paul Nolent; Anne-Gaelle Venier; Olivier Brissaud; Bertille de Barbeyrac; Francis Megraud; Anne-Marie Rogues

doi:10.1016/j.ajic.2015.09.020

Outbreak in newborns of methicillin-resistant Staphylococcus aureus related to the sequence type 5 Geraldine clone

Am J Infect Control. 2016 Feb;44(2):e9-11. doi: 10.1016/j.ajic.2015.09.020. Epub 2015 Nov 14.

Affiliations

¹ Department of Infection Control, Groupe Hospitalier Pellegrin, University Hospital, Bordeaux, France.
² Bacteriology Laboratory, University of Bordeaux, Bordeaux, France; INSERM, U853, Bordeaux, France.
³ Centre National de Référence des Staphylocoques, INSERM U1111, Université Lyon1, Hospices Civils de Lyon, Lyon, France.
⁴ Department of Neonatalogy, Groupe Hospitalier Pellegrin, University Hospital, Bordeaux, France.
⁵ CCLIN Sud-Ouest (HAI control South West France Centre), Bordeaux, France.
⁶ Department of Infection Control, Groupe Hospitalier Pellegrin, University Hospital, Bordeaux, France; INSERM U657, University of Bordeaux, Bordeaux Cedex, France. Electronic address: anne-marie.rogues@chu-bordeaux.fr.

PMID: 26589999
DOI: 10.1016/j.ajic.2015.09.020

Abstract

We describe the first nosocomial outbreak of a toxic shock syndrome-positive methicillin-resistant Staphylococcus aureus (MRSA) sequence type 5 Geraldine clone. Infection control interventions that are usually successful were implemented to control the outbreak. Spread of this virulent MRSA strain highlights the need to be vigilant to MRSA antibiotic susceptibilities.

Keywords: Control; Methicillin-resistant Staphylococcus aureus; Neonatal intensive care unit; Outbreak; Toxic shock syndrome toxin-1; Typing.

MeSH terms

Bacterial Typing Techniques
Child
Cross Infection / epidemiology*
Cross Infection / microbiology
Disease Outbreaks*
Female
Humans
Infant, Newborn
Infection Control*
Intensive Care Units, Neonatal
Male
Methicillin / pharmacology
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus / classification
Methicillin-Resistant Staphylococcus aureus / drug effects
Methicillin-Resistant Staphylococcus aureus / genetics
Methicillin-Resistant Staphylococcus aureus / isolation & purification*
Molecular Typing
Shock, Septic / epidemiology*
Shock, Septic / microbiology
Staphylococcal Infections / epidemiology*
Staphylococcal Infections / microbiology

Substances

Methicillin