Early-onset spastic paraparesis as presenting sign of familial Creutzfeldt-Jakob disease

Parkinsonism Relat Disord. 2015 Dec;21(12):1479-80. doi: 10.1016/j.parkreldis.2015.10.004. Epub 2015 Oct 22.
No abstract available

Keywords: Creutzfeldt–Jakob disease; DTI; PRNP; Spastic paraparesis.

Publication types

  • Case Reports
  • Letter
  • Video-Audio Media

MeSH terms

  • Adult
  • Cognition Disorders / etiology
  • Creutzfeldt-Jakob Syndrome / complications
  • Creutzfeldt-Jakob Syndrome / diagnosis*
  • Creutzfeldt-Jakob Syndrome / genetics
  • Diffusion Tensor Imaging
  • Disease Progression
  • Female
  • Humans
  • Mutation, Missense
  • Paraparesis, Spastic / etiology*
  • Point Mutation
  • Prion Proteins
  • Prions / genetics
  • Speech Disorders / etiology

Substances

  • PRNP protein, human
  • Prion Proteins
  • Prions