γδ T cell-based anticancer immunotherapy: progress and possibilities

Immunotherapy. 2015;7(9):949-51. doi: 10.2217/imt.15.68. Epub 2015 Aug 27.

Authors

Serena Meraviglia¹, Elena Lo Presti¹, Francesco Dieli¹, Giorgio Stassi²

Affiliations

¹ Central Laboratory of Advanced Diagnosis & Biomedical Research (CLADIBIOR), Department of Biopathology, University of Palermo, Palermo, Italy.
² Cellular & Molecular Pathophysiology Laboratory, Department of Surgical & Oncological Sciences, University of Palermo, Via del Vespro 131, Palermo 90134, Italy.

PMID: 26569071
DOI: 10.2217/imt.15.68

No abstract available

Keywords: IFN-γ; IL-17; PD-1; cancer; immunotherapy; tumor-infiltrating lymphocytes; γδ T cells.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cytotoxicity, Immunologic
Humans
Immunotherapy, Adoptive*
Interferon-gamma / metabolism
Interleukin-17 / metabolism
Neoplasms / immunology
Neoplasms / therapy*
Receptors, Antigen, T-Cell, gamma-delta / metabolism*
T-Lymphocytes / immunology*
T-Lymphocytes / transplantation
Tumor Microenvironment

Substances

Interleukin-17
Receptors, Antigen, T-Cell, gamma-delta
Interferon-gamma