A challenging undertaking: Stem cell transplantation for immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome

J Allergy Clin Immunol. 2016 Mar;137(3):953-5.e4. doi: 10.1016/j.jaci.2015.09.030. Epub 2015 Nov 11.

Authors

Zeynep Yesim Kucuk¹, Jack J Bleesing², Rebecca Marsh², Kejian Zhang³, Stella Davies², Alexandra H Filipovich²

Affiliations

¹ Division of Bone Marrow Transplantation and Immune deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address: zeynep.kucuk@cchmc.org.
² Division of Bone Marrow Transplantation and Immune deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
³ Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

PMID: 26559324
DOI: 10.1016/j.jaci.2015.09.030

No abstract available

Publication types

Letter

MeSH terms

Diabetes Mellitus, Type 1 / congenital*
Diabetes Mellitus, Type 1 / genetics
Diabetes Mellitus, Type 1 / immunology
Diabetes Mellitus, Type 1 / therapy
Diarrhea / genetics
Diarrhea / immunology
Diarrhea / therapy*
Forkhead Transcription Factors / genetics*
Genes, X-Linked
Genetic Diseases, X-Linked / genetics
Genetic Diseases, X-Linked / immunology
Genetic Diseases, X-Linked / therapy*
Humans
Immune System Diseases / congenital*
Immune System Diseases / genetics
Immune System Diseases / immunology
Immune System Diseases / therapy
Mutation
Stem Cell Transplantation* / methods
Treatment Outcome

Substances

FOXP3 protein, human
Forkhead Transcription Factors

Supplementary concepts

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome