First outbreak of linezolid-resistant vancomycin-resistant Enterococcus faecium in an Irish hospital, February to September 2014

J Hosp Infect. 2015 Dec;91(4):367-70. doi: 10.1016/j.jhin.2015.09.006. Epub 2015 Oct 3.

Abstract

An outbreak of linezolid-resistant vancomycin-resistant Enterococcus faecium (LRVREfm) occurred in the hepatology ward of a tertiary referral hospital in Ireland between February and September 2014. LRVREfm was isolated from 15 patients; pulsed-field gel electrophoresis confirmed spread of a single clone. This is the first report of an outbreak of linezolid-resistant vancomycin-resistant enterococcus in Ireland.

Keywords: Linezolid-resistant vancomycin-resistant Enterococcus faecium (LRVREfm); Outbreak; Vancomycin-resistant enterococci.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks*
  • Drug Resistance, Bacterial
  • Electrophoresis, Gel, Pulsed-Field
  • Enterococcus faecium / classification
  • Enterococcus faecium / drug effects*
  • Enterococcus faecium / genetics
  • Enterococcus faecium / isolation & purification
  • Gram-Positive Bacterial Infections / epidemiology*
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Ireland / epidemiology
  • Linezolid / pharmacology*
  • Molecular Epidemiology
  • Molecular Typing
  • Tertiary Care Centers
  • Vancomycin-Resistant Enterococci / drug effects*
  • Vancomycin-Resistant Enterococci / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Linezolid