Clinical issue: Prostate cancer is the most common form of cancer in men in Germany; however, there is a distinct difference between incidence and mortality.
Standard treatment: The detection of prostate cancer is based on clinical and laboratory testing using serum prostate-specific antigen (PSA) levels and transrectal ultrasound with randomized biopsy.
Diagnostic work-up: Multiparametric MR imaging of the prostate can provide valuable diagnostic information for detection of prostate cancer, especially after negative results of a biopsy prior to repeat biopsy.
Performance: In addition the use of MR ultrasound fusion-guided biopsy has gained in diagnostic importance and has increased the prostate cancer detection rate.
Achievements and practical recommendations: The prostate imaging reporting and data system (PI-RADS) classification has standardized the reporting of prostate MRI which has positively influenced the acceptance by urologists.
Keywords: Fusion guided biopsy; Magnetic resonance imaging; Multiparametric imaging; Prostate; Prostate imaging reporting and data system.