The PHD2 oxygen sensor paves the way to metastasis

Oncotarget. 2015 Nov 3;6(34):35149-50. doi: 10.18632/oncotarget.6216.

Authors

Anna Kuchnio^{1

2}, Mieke Dewerchin^{1

2}, Peter Carmeliet^{1

2}

Affiliations

¹ Laboratory of Angiogenesis and Neurovascular Link, Department of Oncology, KU Leuven, Leuven, Belgium.
² Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, Leuven, Belgium.

No abstract available

Keywords: breast cancer; cancer associated fibroblast; metastasis; vessel normalization.

Publication types

Editorial

MeSH terms

Animals
Breast Neoplasms / enzymology*
Breast Neoplasms / pathology*
Cell Hypoxia / physiology
Female
Humans
Hypoxia-Inducible Factor-Proline Dioxygenases / metabolism*
Mice
Neoplasm Metastasis
Oxygen / metabolism

Substances

EGLN1 protein, human
Hypoxia-Inducible Factor-Proline Dioxygenases
Oxygen