Statin protects endothelial cell against ischemia reperfusion injury through HMGB1/TLR4 pathway

Int J Cardiol. 2016 Jan 15:203:74. doi: 10.1016/j.ijcard.2015.10.095. Epub 2015 Oct 20.
No abstract available

Keywords: Endothelial cell; HMGB1; Statin.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • DNA / genetics*
  • Gene Expression Regulation / drug effects*
  • HMGB1 Protein / genetics*
  • Humans
  • Myocardial Reperfusion Injury*
  • Phosphatidylinositol 3-Kinases / genetics*
  • Proto-Oncogene Proteins c-akt / genetics*
  • Simvastatin / administration & dosage*

Substances

  • HMGB1 Protein
  • DNA
  • Simvastatin
  • Phosphatidylinositol 3-Kinases
  • Proto-Oncogene Proteins c-akt