Identification and characterization of two new xanthones from Cudrania fruticosa

Bo Liang; Li-Zhen Xu; Shi-Lin Yang; Xiao-Jie Gong

doi:10.1016/S1875-5364(15)30079-0

Identification and characterization of two new xanthones from Cudrania fruticosa

Chin J Nat Med. 2015 Oct;13(10):781-5. doi: 10.1016/S1875-5364(15)30079-0.

Authors

Bo Liang¹, Li-Zhen Xu², Shi-Lin Yang², Xiao-Jie Gong³

Affiliations

¹ Medical College, Dalian University, Dalian 116622, China; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.
² Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.
³ Medical College, Dalian University, Dalian 116622, China. Electronic address: gongxiaojie@dlu.edu.cn.

PMID: 26481379
DOI: 10.1016/S1875-5364(15)30079-0

Abstract

The present study was designed to investigate the chemical constituents of the roots of Cudrania fruticosa Wight. Compounds were isolated by various column chromatographic methods including silica gel, polyamide, sephadex LH-20, and semi-preparative HPLC. Their structures were elucidated by a combination of 1D and 2D NMR techniques, mass spectrometry, and chemical methods. Two new xanthones, Cudraxanthone T and U (1-2), along with four known compounds (3-6) were isolated from the roots of Cudrania fruticosa Wight.

Keywords: Cudrania fruticosa; Cudraxanthone T; Cudraxanthone U; Xanthones.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Molecular Structure
Moraceae / chemistry*
Plant Extracts / chemistry*
Plant Roots / chemistry
Xanthones / chemistry
Xanthones / isolation & purification*

Substances

Plant Extracts
Xanthones