Vascular uterine abnormalities: Comparison of imaging findings and clinical outcomes

Eur J Radiol. 2015 Dec;84(12):2485-91. doi: 10.1016/j.ejrad.2015.10.005. Epub 2015 Oct 23.

Abstract

Objective: To retrospectively compare the imaging findings and the outcomes for patients with vascular uterine abnormalities (VUA) and to identify prognostic factors.

Material and methods: Between 2007 and 2012, 38 patients with vaginal bleeding and abnormal ultrasonographic (US) findings consistent with acquired VUA were consecutively included (mean age 31.6 years, range 19-62). Follow-up was 32 months in mean (1-78 months). Seventeen women (44.7%) started bleeding immediately after curettage, spontaneous miscarriage, trophoblastic disease, or section scars, with the remainder starting bleeding after 8 days to 2 years. All US, CT (n=2), MR (n=5) and angiographic (n=26) images were reviewed and compared to medical reports in order to identify severe VUA requiring treatment, and predictive factors.

Results: No information about severity was provided by US, MRI or CT. Twelve patients were successfully managed conservatively. Angiography identified 6 non-severe VUA, corresponding to an isolated uterine hyperemia, and 20 severe VUA, corresponding to an association of a nidus and early venous drainage. Recurrences were more often observed for severe VUA (p=0.001). The hemoglobin level was significantly lower (below 11 g/L) in these cases (p=0.004). Recurrences were significantly more frequently observed for patients with history of dilatation and curettage (p=0.02). Hysterectomy was performed for three patients only (8%). Among the women who wished to have children, 14 (77.8%) were pregnant after 9 months in mean (range 2-23).

Conclusions: Recurrence happens more frequently after curettage and in case of anemia or severe VUA findings on angiography, justifying adequate embolization for these patients.

Keywords: Arteriovenous malformation; Curettage; Embolization; Pregnancy; Uterus hemorrhage.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Anemia / complications
  • Arteriovenous Malformations / complications
  • Arteriovenous Malformations / therapy*
  • Curettage
  • Diagnostic Imaging*
  • Embolization, Therapeutic*
  • Female
  • Follow-Up Studies
  • Humans
  • Hysterosalpingography
  • Magnetic Resonance Imaging
  • Middle Aged
  • Pregnancy
  • Recurrence
  • Retrospective Studies
  • Severity of Illness Index
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography
  • Urogenital Abnormalities / complications
  • Urogenital Abnormalities / therapy*
  • Uterine Hemorrhage / complications
  • Uterine Hemorrhage / therapy
  • Uterus / abnormalities*
  • Uterus / diagnostic imaging
  • Uterus / pathology
  • Young Adult

Supplementary concepts

  • Uterine Anomalies