Synchronous pituitary adenoma and pituicytoma

Hum Pathol. 2016 Jan;47(1):138-43. doi: 10.1016/j.humpath.2015.08.017. Epub 2015 Sep 16.

Abstract

Pituicytoma is a rare benign neoplasm arising in the sellar region, usually found in the posterior lobe and/or pituitary stalk. Here, we report the case of a 67-year-old woman who presented with bitemporal hemianopsia and visual impairment accompanied by mildly elevated prolactin. Pathologic and molecular examination of the tissue removed transsphenoidally revealed 2 distinct tumors: pituitary adenoma and pituicytoma. To the best of our knowledge, histologically proven pituicytoma and pituitary adenoma have never been reported together.

Keywords: MRI; Pituicyte; Pituicytoma; Pituitary adenoma; TTF1.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / blood
  • Adenoma / complications
  • Adenoma / genetics
  • Adenoma / pathology*
  • Adenoma / surgery
  • Aged
  • Biomarkers, Tumor / blood
  • Biomarkers, Tumor / genetics
  • Biopsy
  • DNA Methylation
  • Endoscopy
  • Female
  • Hemianopsia / etiology
  • Humans
  • Immunohistochemistry
  • Magnetic Resonance Imaging
  • Neoplasms, Multiple Primary / blood
  • Neoplasms, Multiple Primary / complications
  • Neoplasms, Multiple Primary / genetics
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / surgery
  • Pituitary Neoplasms / blood
  • Pituitary Neoplasms / complications
  • Pituitary Neoplasms / genetics
  • Pituitary Neoplasms / pathology*
  • Pituitary Neoplasms / surgery
  • Prolactin / blood
  • Visual Fields

Substances

  • Biomarkers, Tumor
  • Prolactin