Nail lichen striatus: report of seven cases and review of the literature

Int J Dermatol. 2015 Nov;54(11):1255-60. doi: 10.1111/ijd.12643.

Abstract

Background: Nail involvement in lichen striatus (LS) is rare and has not been documented extensively.

Objectives: This study describes the clinical and histological features, response to treatment, and follow-up in seven patients with nail LS.

Methods: We reviewed seven cases of nail LS between 2006 and 2012 at the Dermatology Department, Yeouido St Mary's Hospital, Seoul, South Korea.

Results: The median patient age was 11 years (range: 4-33 years), and the female:male ratio was 3:4. All patients had both typical skin lesions and nail abnormalities. In these cases, LS usually involved a single digit (n = 5). The most common nail change was longitudinal fissuring (n = 4). We actively treated both skin and nail lesions from the time of diagnosis. Most nail lesions resolved within a mean of four months of the initiation of treatment.

Conclusions: Nail involvement in LS is rare; this case series highlights the associated nail changes. We emphasize that early accurate diagnosis and treatment may be beneficial in reducing nail deformities in patients with nail involvement.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Child
  • Child, Preschool
  • Drug Therapy, Combination
  • Female
  • Foot Dermatoses / drug therapy
  • Foot Dermatoses / pathology*
  • Hand Dermatoses / drug therapy
  • Hand Dermatoses / pathology*
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / therapeutic use
  • Lichenoid Eruptions / drug therapy
  • Lichenoid Eruptions / pathology*
  • Male
  • Nail Diseases / drug therapy
  • Nail Diseases / pathology*
  • Tacrolimus / therapeutic use
  • Triamcinolone Acetonide / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents
  • Triamcinolone Acetonide
  • Tacrolimus