Clinical usefulness of transabdominal ultrasonography prior to patency capsule for suspected small-bowel strictures

Scand J Gastroenterol. 2016 Mar;51(3):281-7. doi: 10.3109/00365521.2015.1095942. Epub 2015 Oct 14.

Abstract

Objective: Patency capsule (PC) examination has made it possible to perform capsule endoscopy (CE) in patients with a suspected small-bowel stricture. However, PC has some drawbacks, so we assessed the usefulness of transabdominal ultrasonography (TUS) prior to PC in patients with suspected small-bowel strictures to avoid unnecessary PC examination.

Patients and methods: Fifty-two patients who underwent TUS prior to PC were enrolled in this study. TUS findings were classified as follows: intestinal narrowing and distension at the oral side (Type A); extensive bowel wall thickening (Type B); focal bowel wall thickening (Type C) or no abnormality detected (Type D). We evaluated the TUS and PC findings for the detection of small-bowel strictures.

Results: Double-balloon endoscopy (DBE) revealed small-bowel strictures in 13 of 50 patients (26%). TUS yielded Type B or C findings in 12 of 13 patients (92%), while PC revealed strictures in all 13 patients. In Crohn's disease (CD) patients with Type B TUS findings, 8 of 9 (89%) had small-bowel strictures on DBE. However, only two of six non-CD patients (33%) with Type B TUS findings had small-bowel strictures. The incidence of Type B strictures was significantly higher in CD patients.

Conclusions: CD patients with Type B TUS findings should not undergo PC or CE because of the high rate of small-bowel strictures. Non-CD patients diagnosed with Type B TUS strictures, as well as patients diagnosed with Type C or D strictures should undergo CE after confirming small-bowel patency using PC.

Keywords: Capsule endoscopy; Crohn’s disease; double-balloon endoscopy; small-bowel disease.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Capsule Endoscopy / methods*
  • Constriction, Pathologic / classification
  • Constriction, Pathologic / diagnostic imaging
  • Constriction, Pathologic / etiology
  • Crohn Disease / complications
  • Crohn Disease / diagnostic imaging
  • Crohn Disease / pathology*
  • Double-Balloon Enteroscopy
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Humans
  • Intestinal Obstruction / diagnostic imaging*
  • Intestinal Obstruction / etiology
  • Intestine, Small / diagnostic imaging*
  • Intestine, Small / pathology*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sensitivity and Specificity
  • Ultrasonography
  • Young Adult