A case of lineage switch from B-cell acute lymphoblastic leukaemia to acute myeloid leukaemia. Role of subclonal/clonal gene mutations

Br J Haematol. 2016 Aug;174(4):648-51. doi: 10.1111/bjh.13800. Epub 2015 Oct 12.
No abstract available

Keywords: DNA mutation; acute leukaemia; lineage switch.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cell Lineage / genetics*
  • Clone Cells / pathology*
  • Female
  • Gene Rearrangement
  • Genes, Immunoglobulin Heavy Chain
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Mutation*
  • Neoplasm, Residual / genetics
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Receptors, Antigen, T-Cell / genetics
  • Sequence Analysis, DNA

Substances

  • Receptors, Antigen, T-Cell