A Hemimethyl-Substituted Cucurbit[7]uril Derived from 3α-Methyl-glycoluril

Org Lett. 2015 Oct 16;17(20):5072-5. doi: 10.1021/acs.orglett.5b02588. Epub 2015 Oct 8.

Abstract

A novel hemimethyl-substituted cucurbit[7]uril (HMeQ[7]) derived from 3α-methyl-glycoluril has been prepared. HMeQ[7] is readily soluble in both water and dimethyl sulfoxide (DMSO) and displays not only host-guest interaction properties similar to those of the normal cucurbit[7]uril but also unusual properties in DMSO.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemical synthesis*
  • Alkynes / chemistry
  • Crystallography, X-Ray
  • Dimethyl Sulfoxide / chemistry
  • Imidazoles / chemical synthesis*
  • Imidazoles / chemistry
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Thermodynamics
  • Water

Substances

  • Alkynes
  • Imidazoles
  • Water
  • glycoluril
  • Dimethyl Sulfoxide