Autoimmune pancreatitis with extraocular muscles involvement

J Pak Med Assoc. 2015 Oct;65(10):1125-7.

Abstract

Autoimmune pancreatitis is characterised by diffuse enlargement of pancreas, narrowing of pancreatic duct, lymphoplasmacytic infiltrations and fibrosis. The disease is responsive to corticosteroid. We report the case of a 32-year-old male who presented with unilateral exophthalmos and obstructive jaundice secondary to pancreatic head mass and biliary tract stricture. Serum immunoglobulin G level was raised with a very high immunoglobulin G4 subclass. Ophthalmological imaging revealed unilateral thickening of extraocular muscles. The patient responded well to corticosteroid with resolution of biliary strictures, pancreatic head mass and exophthalmos.

Keywords: Autoimmune pancreatitis; IgG4-related systemic disease; Exophthalmos.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoimmune Diseases / complications
  • Autoimmune Diseases / diagnosis*
  • Exophthalmos / diagnostic imaging*
  • Exophthalmos / etiology*
  • Humans
  • Male
  • Oculomotor Muscles*
  • Pancreatitis, Chronic / complications*
  • Pancreatitis, Chronic / diagnosis*