[Influence of weight gain during the first year after kidney transplantation in the survival of grafts and patients]

Rev Med Chil. 2015 Aug;143(8):961-70. doi: 10.4067/S0034-98872015000800001.
[Article in Spanish]

Abstract

Background: After receiving a kidney allograft, patients tend to gain weight acquiring the risk associated with overweight and obesity.

Aim: To compare the evolution during 10 years after transplantation of patients who gained more than 15% of their initial weight during the first year after receiving the graft with those who did not experience this increase.

Material and methods: Cohort study of 182 patients transplanted in a single hospital between 1981 and 2003. Demographic data, weight gain during the first year, drugs used, complications and evolution of patients and grafts were recorded.

Results: Seventy two patients gained more than 15% of their weight during the first year. These were discharged after receiving the graft with a lower serum creatinine than their counterparts (1.46 ± 0.71 and 1.97 ± 1.74 mg/dl respectively, p = 0.02). Ten years mortality with a functioning kidney was higher among weight gainers (25 and 12.7% respectively, p = 0.03). No other differences were observed between groups.

Conclusions: Patients who gained more than 15% of their initial weight during the first year after receiving a kidney graft have a higher 10 years mortality with a functioning kidney.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Cohort Studies
  • Creatinine / blood
  • Female
  • Follow-Up Studies
  • Graft Survival*
  • Humans
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / mortality*
  • Male
  • Middle Aged
  • Patient Readmission / statistics & numerical data
  • Survival Analysis
  • Time Factors
  • Weight Gain*

Substances

  • Creatinine