Intestinal amoebiasis in a patient with acute graft-versus-host disease after allogeneic bone marrow transplantation successfully treated by metronidazole

Transpl Infect Dis. 2015 Dec;17(6):886-9. doi: 10.1111/tid.12460. Epub 2015 Nov 25.

Abstract

Amoebiasis has rarely been reported in patients undergoing hematopoietic stem cell transplantation, although it is a world-wide infection and extremely common. We present a case of intestinal amoebiasis unexpectedly revealed by colonoscopy after allogeneic bone marrow transplantation from a human leukocyte antigen-mismatched unrelated donor for acute myeloid leukemia arising from chronic myelomonocytic leukemia and successfully treated by metronidazole.

Keywords: Entamoeba histolytica; HSCT; bone marrow transplantation; intestinal amoebiasis.

Publication types

  • Case Reports

MeSH terms

  • Antiprotozoal Agents / therapeutic use*
  • Bone Marrow Transplantation / adverse effects*
  • Dysentery, Amebic / drug therapy*
  • Dysentery, Amebic / etiology
  • Graft vs Host Disease / complications*
  • Humans
  • Immunocompromised Host
  • Male
  • Metronidazole / therapeutic use*
  • Middle Aged

Substances

  • Antiprotozoal Agents
  • Metronidazole