Metal ion levels in ceramic-on-ceramic THR with modular necks: analysis of cobalt and chromium serum levels in 30 healthy hip patients

Hip Int. 2015 Sep-Oct;25(5):484-7. doi: 10.5301/hipint.5000257. Epub 2015 Sep 9.

Abstract

Background: Modular necks in total hip replacement (THR) can be a source of metal ion release. There are no data to date on the level of cobalt and chromium ions in the serum of patients with a cobalt-chrome stem and a titanium modular neck.

Methods: Serum ion levels were measured in healthy volunteers with a well-functioning ceramic-on-ceramic THR.

Results: Average cobalt in serum was 1.21 µg/l for unilateral THR and 2.2 µg/l for bilateral THR. No patient had cobalt levels higher than 2.4 µg/l. No patient had measurable chromium levels. There were no differences in cobalt levels for hips with short necks versus hips with long necks.

Conclusions: The hybrid THR Profemur® Xm - Procotyl® L with a titanium modular neck on a cobalt-chrome stem design shows no signs of abnormal toxic ion levels (cobalt or chromium) in a randomly selected group of well-functioning hip patients.

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Hip / methods*
  • Ceramics
  • Chromium / blood*
  • Chromium Alloys / chemistry*
  • Cobalt / blood*
  • Cohort Studies
  • Female
  • Hip Prosthesis*
  • Humans
  • Ions / blood
  • Male
  • Middle Aged
  • Patient Safety
  • Prospective Studies
  • Prosthesis Design / methods*
  • Reference Values

Substances

  • Chromium Alloys
  • Ions
  • Chromium
  • Cobalt