Serum Ionized Calcium Quantification for Staging Canine Periodontal Disease: A Preliminary Study

Top Companion Anim Med. 2015 Jun;30(2):48-50. doi: 10.1053/j.tcam.2015.07.002. Epub 2015 Jul 8.

Abstract

Periodontal diseases (PD) are infectious, inflammatory, progressive diseases of the oral cavity affecting people and dogs. PD takes 2 forms: gingivitis and periodontitis. Diagnosing or staging PD can be achieved only with dental x-rays and periodontal probing, both of which require the use of general anesthesia in dogs. This study aimed to determine whether serum ionized calcium ([iCa(2+)]) levels can be useful in preliminary PD staging in dogs. A sample of 40 dogs (n = 40) was divided into 4 groups (n = 10 each) based on the following PD stages: G1 (gingivitis), G2 (initial periodontitis), G3 (moderate periodontitis), and G4 (severe periodontitis). The groups were then subjected to [iCa(2+)] quantification. Statistically significant differences were observed between PD stages and [iCa(2+)] for all stages except G3 and G4. Therefore, this parameter can be used as an additional tool to establish and monitor preliminary PD status.

Keywords: diagnostic; dog; periodontal disease; serum ionized calcium; staging.

Publication types

  • Evaluation Study

MeSH terms

  • Animals
  • Biomarkers / blood
  • Calcium / blood*
  • Dental Calculus / veterinary
  • Dog Diseases / blood
  • Dog Diseases / diagnosis*
  • Dog Diseases / diagnostic imaging
  • Dog Diseases / pathology
  • Dogs
  • Female
  • Male
  • Periodontal Diseases / diagnosis
  • Periodontal Diseases / veterinary*
  • Periodontal Index
  • Severity of Illness Index

Substances

  • Biomarkers
  • Calcium