Cesarean delivery among women with prolonged labor induction

J Perinat Med. 2016 Oct 1;44(7):759-766. doi: 10.1515/jpm-2014-0357.

Abstract

Objective: The objective of this study was to determine characteristics associated with cesarean delivery among women with labor induction lasting over 24 h.

Study design: Women with live singleton pregnancies without prior cesarean delivery undergoing a labor induction lasting >24 h between September 2006 and March 2009 at Duke University Hospital were identified. Collected variables were compared between subjects by mode of delivery. A multivariate logistic regression model for the outcome cesarean delivery was constructed separately for nulliparous and parous women.

Results: There were 303 women who met inclusion criteria. The overall cesarean delivery rate was 57% (n=172) and remained constant with time (P=0.15, test-for-trend). Nulliparous women having a cesarean delivery were more likely to be obese [adjusted OR (aOR) 2.00; 95% CI 1.05, 3.80] and have a larger fetus [aOR 1.11 (aOR for every 100 g increase in birthweight), 95% CI 1.03, 1.20] compared to those having a vaginal delivery.

Conclusion: Increasing BMI and birthweight were independent predictors of cesarean delivery among nulliparous women with prolonged labor induction. Despite this, after 24 h of labor induction, the overall mean cesarean delivery rate remained constant at 57%, and did not change with time. Among women having a vaginal delivery following a prolonged labor induction, we saw high rates of shoulder dystocia, operative vaginal delivery and severe perineal laceration.

MeSH terms

  • Adult
  • Cesarean Section*
  • Cohort Studies
  • Female
  • Humans
  • Infant, Newborn
  • Labor, Induced / adverse effects*
  • Logistic Models
  • Male
  • Oxytocin / therapeutic use
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Young Adult

Substances

  • Oxytocin