Graphene-Gold Metasurface Architectures for Ultrasensitive Plasmonic Biosensing

Shuwen Zeng; Kandammathe Valiyaveedu Sreekanth; Jingzhi Shang; Ting Yu; Chih-Kuang Chen; Feng Yin; Dominique Baillargeat; Philippe Coquet; Ho-Pui Ho; Andrei V Kabashin; Ken-Tye Yong

doi:10.1002/adma.201501754

Graphene-Gold Metasurface Architectures for Ultrasensitive Plasmonic Biosensing

Adv Mater. 2015 Oct 28;27(40):6163-9. doi: 10.1002/adma.201501754. Epub 2015 Sep 9.

Authors

Shuwen Zeng^{1

2}, Kandammathe Valiyaveedu Sreekanth³, Jingzhi Shang³, Ting Yu³, Chih-Kuang Chen⁴, Feng Yin², Dominique Baillargeat^{1

5}, Philippe Coquet^{1

6}, Ho-Pui Ho⁷, Andrei V Kabashin⁸, Ken-Tye Yong^{1

2}

Affiliations

¹ CINTRA CNRS/NTU/THALES, UMI 3288, Research Techno Plaza, 50 Nanyang Drive, Border X Block, Singapore, 637553, Singapore.
² School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, 639798, Singapore.
³ Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore.
⁴ The Polymeric Biomaterials Lab, Feng Chia University, Taichung, 40724, Taiwan.
⁵ XLIM UMR CNRS 7252, Université de Limoges/CNRS, Limoges, 87060, France.
⁶ Institut d'Electronique, de Microélectronique et de Nanotechnologie (IEMN), CNRS UMR 8520 - Université de Lille 1, 59650, Villeneuve d'Ascq, France.
⁷ Department of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong, 999077.
⁸ Aix Marseille University, CNRS, LP3 UMR 7341, Campus de Luminy, 163 Avenue de Luminy, Case 917, 13288, Marseille cedex 9, France.

PMID: 26349431
DOI: 10.1002/adma.201501754

Abstract

Graphene-gold metasurface architectures that can provide significant gains in plasmonic detection sensitivity for trace-amount target analytes are reported. Benefiting from extreme phase singularities of reflected light induced by strong plasmon-mediated energy confinements, the metasurface demonstrates a much-improved sensitivity to molecular bindings nearby and achieves an ultralow detection limit of 1 × 10(-18) m for 7.3 kDa 24-mer single-stranded DNA.

Keywords: biosensors; metasurfaces; plasmonic sensing; surface plasmon polaritons.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA, Single-Stranded / analysis
Electromagnetic Phenomena
Gold / chemistry*
Graphite / chemistry*
Surface Plasmon Resonance*
Surface Properties

Substances

DNA, Single-Stranded
Gold
Graphite