1 Department of Cardiology (M.L., Z.F.), Jiangsu Province Hospital of Traditional Chinese Medicine, The Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210029, China; and Department of Medicine, Physiology, and Biophysics (M.L., Q.Y.), Centre for Diabetes Research and Treatment, Center for Epigenetics and Metabolism, University of California Irvine, Irvine, California 92697.