Prevalence of nasopharyngeal pneumococcal colonization in children and antimicrobial susceptibility profiles of carriage isolates

Int J Infect Dis. 2015 Oct:39:50-52. doi: 10.1016/j.ijid.2015.08.010. Epub 2015 Sep 3.

Abstract

Nasopharyngeal (NP) pneumococcal carriage predisposes children to pneumococcal infections. Defining the proportion of pneumococcal isolates that are antibiotic-resistant enables the appropriate choice of empiric therapies. The antibiogram of NP carriage isolates derived from a pediatric population following the introduction of the 13-valent pneumococcal conjugate vaccine was defined in this study.

Keywords: Streptococcus pneumoniae; antimicrobial resistance; colonization; epidemiology.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / pharmacology
  • Carrier State / microbiology
  • Child
  • Child, Preschool
  • Drug Resistance, Bacterial*
  • Humans
  • Infant
  • Infant, Newborn
  • Nasopharynx / microbiology*
  • Pneumococcal Infections / epidemiology
  • Pneumococcal Infections / microbiology*
  • Pneumococcal Vaccines
  • Prevalence
  • Streptococcus pneumoniae / drug effects*
  • Streptococcus pneumoniae / isolation & purification*

Substances

  • 13-valent pneumococcal vaccine
  • Anti-Bacterial Agents
  • Pneumococcal Vaccines