Autophagic death probed by photodynamic therapy

Autophagy. 2015;11(10):1941-3. doi: 10.1080/15548627.2015.1078960.

Abstract

The high degree of selectivity for photodamage to subcellular organelles can provide a means for evaluation of autophagic death pathways. While many current reports rely on ambiguous criteria, there are glimmers of unequivocal evidence.

Keywords: apoptosis; autophagy; lysosomes; mitochondria; photodynamic.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Apoptosis / drug effects*
  • Autophagy / drug effects*
  • Humans
  • Mitochondria / drug effects*
  • Mitochondria / metabolism
  • Organelles / drug effects
  • Organelles / metabolism
  • Photochemotherapy* / methods
  • Photosensitizing Agents / pharmacology*

Substances

  • Photosensitizing Agents