[Linear immunoglobulin A bullous dermatosis: Two cases report]

Arch Argent Pediatr. 2015 Oct;113(5):e279-82. doi: 10.5546/aap.2015.e279.
[Article in Spanish]

Abstract

Linear immunoglobulin A bullous dermatosis is a rare entity with frequent spontaneous resolution. It usually presents in children with average age of 4.5 years. Its incidence is about 0.5-2.3 cases/million individuals/year. It is, after dermatitis herpetiformis, the most frequent paediatric blister disorder. It usually appears in bouts with acute development of vesicles in strings of pearls; affecting the perioral area and genitalia. Diagnosis is based on the clinical signs and symptoms and biopsy of the skin with subepidermal blister and a linear band of immunoglobulin A in the direct immunofluorescence. Often, diagnosis is made late because of the unawareness of this disease.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Linear IgA Bullous Dermatosis / drug therapy
  • Linear IgA Bullous Dermatosis / pathology*
  • Male