Malignant Middle Cerebral Artery Infarction Resulting from Dissection of Middle Cerebral Artery

Kenichi Sakuta; Renpei Sengoku; Hidetaka Mitsumura; Yu Kono; Issei Kan; Shogo Kaku; Yasuyuki Iguchi

doi:10.1016/j.jstrokecerebrovasdis.2015.04.008

Malignant Middle Cerebral Artery Infarction Resulting from Dissection of Middle Cerebral Artery

J Stroke Cerebrovasc Dis. 2015 Oct;24(10):e287-9. doi: 10.1016/j.jstrokecerebrovasdis.2015.04.008. Epub 2015 Aug 13.

Authors

Kenichi Sakuta¹, Renpei Sengoku², Hidetaka Mitsumura³, Yu Kono³, Issei Kan⁴, Shogo Kaku⁴, Yasuyuki Iguchi³

Affiliations

¹ Department of Neurology, The Jikei University School of Medicine, Tokyo, Japan. Electronic address: kenichisakuta@yahoo.co.jp.
² Department of Neurology, The Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
³ Department of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
⁴ Department of Neurosurgery, The Jikei University School of Medicine, Tokyo, Japan.

PMID: 26279098
DOI: 10.1016/j.jstrokecerebrovasdis.2015.04.008

Abstract

A 30-year-old man presented with headache, left hemiparesis, and uncal herniation. Magnetic resonance imaging showed acute infarction in the right middle cerebral artery (MCA). Lifesaving craniotomy proceeded because of the uncal herniation. Assessment of brain tissue led to a diagnosis of MCA dissection. His skin biopsy showed ultrastructural abnormalities of dermal connective tissue. This is the unique case that dissection was diagnosed from both a biopsy specimen of the MCA and the dermal connective tissue.

Keywords: Middle cerebral artery; acute ischemic stroke; dissection; malignant middle cerebral artery infarction; skin biopsy.

Publication types

Case Reports

MeSH terms

Adult
Cerebral Angiography
Humans
Infarction, Middle Cerebral Artery / diagnosis
Infarction, Middle Cerebral Artery / etiology*
Intracranial Aneurysm / complications*
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Male
Middle Cerebral Artery / pathology*