A mosquito mediator of parasite-induced immune priming

Maria L Simões; George Dimopoulos

doi:10.1016/j.pt.2015.07.004

A mosquito mediator of parasite-induced immune priming

Trends Parasitol. 2015 Sep;31(9):402-4. doi: 10.1016/j.pt.2015.07.004. Epub 2015 Aug 5.

Authors

Maria L Simões¹, George Dimopoulos²

Affiliations

¹ W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
² W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. Electronic address: gdimopo1@jhu.edu.

Abstract

Immune memory is a central feature of the mammalian adaptive immune system. The more primitive innate immune system of insects has also been shown to comprise memory, or immune priming. A recent study has shed new light on how Plasmodium primes the mosquito immune system for greater resistance to a subsequent infection with the same pathogen.

Keywords: Plasmodium; immune priming; memory; mosquito.

MeSH terms

Animals
Anopheles / immunology*
Anopheles / parasitology*
Immunity, Innate*
Models, Biological
Plasmodium / immunology*

Abstract

MeSH terms

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