An autopsy report of acute myocardial infarction with hypertrophic obstructive cardiomyopathy-like heart

Cardiovasc Pathol. 2015 Nov-Dec;24(6):405-7. doi: 10.1016/j.carpath.2015.07.004. Epub 2015 Jul 11.

Abstract

An 84-year-old woman, who was followed up as hypertrophic obstructive cardiomyopathy (HOCM) in a local hospital, was transferred to our center because of anterior chest pain and diagnosed with acute myocardial infarction (MI). Coronary angiography showed total occlusion of the mid-left anterior descending, and flow was restored after endovascular thrombectomy. An autopsy was performed after she died on hospital day 6. At autopsy, there was no significant stenosis in this vessel and the absence of plaque rupture was confirmed. Likewise, it was unclear asymmetric hypertrophy at autopsy, it could not deny that a sigmoid deformity of the basal septum occurs in elderly patients and can mimic the asymmetric septal hypertrophy of hypertrophic cardiomyopathy. MI was thought to be caused by coronary spasm or squeezing in HOCM-like heart. Therefore, it may be necessary antithrombosis therapy in HOCM-like patients with no history of paroxysmal atrial fibrillation.

Keywords: Acute myocardial infarction; Autopsy; Hypertrophic obstructive cardiomyopathy.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Autopsy
  • Biopsy
  • Cardiomyopathy, Hypertrophic / complications
  • Cardiomyopathy, Hypertrophic / pathology*
  • Cause of Death
  • Coronary Angiography
  • Electrocardiography
  • Fatal Outcome
  • Female
  • Humans
  • Myocardial Infarction / etiology
  • Myocardial Infarction / pathology*
  • Myocardial Infarction / therapy
  • Myocardium / pathology*
  • Percutaneous Coronary Intervention
  • Thrombectomy
  • Treatment Outcome
  • Ultrasonography, Interventional