Targeting aggressive cancers with an artificial sweetener: could saccharin be a lead compound in anticancer therapy?

Future Oncol. 2015;11(15):2117-9. doi: 10.2217/fon.15.137.
No abstract available

Keywords: anticancer therapies; carbonic anhydrase IX and XII; saccharin; tumor hypoxia.

MeSH terms

  • Antigens, Neoplasm / genetics
  • Antineoplastic Agents / therapeutic use
  • Carbonic Anhydrase IX
  • Carbonic Anhydrases / genetics
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / pathology
  • Saccharin / therapeutic use*
  • Sweetening Agents / therapeutic use

Substances

  • Antigens, Neoplasm
  • Antineoplastic Agents
  • Sweetening Agents
  • CA9 protein, human
  • Carbonic Anhydrase IX
  • Carbonic Anhydrases
  • carbonic anhydrase XII
  • Saccharin