Trichosporon faecale invasive infection in a patient with severe aplastic anemia: Efficacy of voriconazole and liposomal amphotericin B before neutrophil recovery

Baptiste Pérard; Amandine Rougeron; Simon Favre; Isabelle Accoceberry; Stéphane Vigouroux; Catherine Mohr; Noël Milpied

doi:10.1016/j.mmcr.2015.06.003

Trichosporon faecale invasive infection in a patient with severe aplastic anemia: Efficacy of voriconazole and liposomal amphotericin B before neutrophil recovery

Med Mycol Case Rep. 2015 Jul 2:9:12-4. doi: 10.1016/j.mmcr.2015.06.003. eCollection 2015 Sep.

Authors

Baptiste Pérard¹, Amandine Rougeron², Simon Favre¹, Isabelle Accoceberry², Stéphane Vigouroux¹, Catherine Mohr³, Noël Milpied³

Affiliations

¹ Service d'Hématologie et de Thérapie Cellulaire, CHU Haut-Lévêque, Bordeaux, France.
² Laboratoire de Parasitologie Mycologie, CHU Pellegrin, Bordeaux, France.
³ Service d'Hématologie et de Thérapie Cellulaire, CHU Haut-Lévêque, Bordeaux, France ; Université Bordeaux Segalen, Bordeaux, France.

Abstract

We report a case of a 51-year old man with a severe aplastic anemia who developed an invasive trichosporonosis to Trichosporon faecale with fungemia and skin lesions during severe neutropenia. The treatment was successful before neutrophil recovery with a combination of voriconazole and liposomal amphotericin B.

Keywords: Aplastic anemia; Hematological disease; Invasive infection; Trichosporon faecale.