Seroprevalence of antibody to TgGRA7 antigen of Toxoplasma gondii in livestock animals from Western Java, Indonesia

Parasitol Int. 2015 Dec;64(6):484-6. doi: 10.1016/j.parint.2015.07.004. Epub 2015 Jul 18.

Abstract

Toxoplasmosis is a concern in both human and veterinary medicine, and the consumption of undercooked meat infected with Toxoplasma gondii is a major risk factor in human infection. Establishing the prevalence of the parasite in food-producing livestock is essential to reduce the risk of human infection. This study aimed to determine the prevalence of T. gondii-specific antibodies in cattle and pigs in Western Java, Indonesia. Serum samples from 598 cattle and 205 pigs from 18 locations in Western Java, Indonesia, were tested for antibodies to T. gondii using an enzyme-linked immunosorbent assay (ELISA). The seroprevalence was 14.6% in pigs and 7.4% in cattle, and significantly more pigs were seropositive compared with cattle (p<0.01). The results of this study suggest that consumption of undercooked meat should be regarded as an important source of infection in people. This study suggests that the risk factors for T. gondii infection in livestock appeared to be different in each location because geographical variation in seroprevalence was observed. The results of this study will facilitate further research to identify and control risk factors for T. gondii in the surveyed locations.

Keywords: Cattle; ELISA; Indonesia; Pig; TgGRA7; Toxoplasma gondii.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Protozoan / blood*
  • Antigens, Protozoan / immunology*
  • Cattle / parasitology*
  • Cattle Diseases / epidemiology*
  • Cattle Diseases / parasitology
  • Enzyme-Linked Immunosorbent Assay / veterinary
  • Geography
  • Humans
  • Indonesia / epidemiology
  • Livestock / immunology
  • Livestock / parasitology
  • Meat / parasitology
  • Protozoan Proteins / immunology*
  • Seroepidemiologic Studies
  • Swine / parasitology*
  • Swine Diseases / epidemiology*
  • Swine Diseases / parasitology
  • Toxoplasma / immunology
  • Toxoplasmosis, Animal / epidemiology*
  • Toxoplasmosis, Animal / immunology
  • Toxoplasmosis, Animal / parasitology

Substances

  • Antibodies, Protozoan
  • Antigens, Protozoan
  • GRA7 protein, Toxoplasma gondii
  • Protozoan Proteins