Gene Mutation Profiling of Breast Cancers for Clinical Decision Making: Drivers and Passengers in the Cart Before the Horse

JAMA Oncol. 2015 Aug;1(5):569-70. doi: 10.1001/jamaoncol.2015.0761.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor / genetics*
  • Biopsy
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / pathology
  • Class I Phosphatidylinositol 3-Kinases
  • DNA Mutational Analysis* / trends
  • Diffusion of Innovation
  • Female
  • Gene Expression Profiling* / trends
  • Genetic Predisposition to Disease
  • Humans
  • Molecular Targeted Therapy
  • Mutation*
  • Phenotype
  • Phosphatidylinositol 3-Kinases / genetics
  • Precision Medicine* / trends
  • Predictive Value of Tests
  • Reproducibility of Results

Substances

  • Biomarkers, Tumor
  • Phosphatidylinositol 3-Kinases
  • Class I Phosphatidylinositol 3-Kinases
  • PIK3CA protein, human